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Alfuzosin HCL (Generic Uroxatral)

Alfuzosin HCL (Generic Uroxatral)

Description

Alfuzosin drug is used in men to treat symptoms of an enlarged prostate, which include difficulty urinating (dribbling, hesitation, incomplete bladder emptying ,weak stream), painful urination, and urinary frequency and urgency.

Alfuzosin drug is in a class of medications called alpha blockers which do work by relaxing the muscles in the prostate and bladder to allow urine to flow more easily.
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Alfuzosin HCL (Generic Uroxatral) 10mg
Manufacturer: India
Brand name: Uroxatral
Generic name: Alfuzosin HCL
Delivery time: Approx. 14-21 days
Quantity
 		 Price per item Price
 		 Returning customer price Bonuses
 		  
50 tab(s) $0.66 $33.00 $29.50  
90 tab(s) $0.61 $54.90 $49.50  
200 tab(s) $0.55 $110.00 $98.00 Free shipping 
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Alfuzosin  is a prescription drug used for the treatment of benign prostatic hyperplasia (BPH). BPH is a noncancerous enlargement of the prostate gland. Symptoms include frequent urination and urinary retention.
 
Other Names - Alfuzosin is marketed in the U.S. by Sanofi-Aventis under the brand name Uroxatral. Outside of the United States, Alfuzosin is marketed as Xatral.

Uses
Alfuzosin is used to relieve the symptoms of BPH.
How Alfuzosin is Taken

Alfuzosin is available in 10 mg tablets. The recommended dose is one tablet daily taken immediately after the same meal each day.

How Alfuzosin Works
The symptoms of BPH, such as increased urination, urination throughout the night, weak urine stream, hesitancy and incomplete emptying of bladder, are attributed to both anatomical and functional causes. The anatomical cause is related to the size of the prostate. The functional cause is related to muscle tone in the prostate, the bladder, and the urethra, which is the vessel through which urine exits the body (see diagram above). Alpha adrenergic receptors control the tone of this muscle. Stimulation of these receptors increases muscle tone and causes many of the symptoms of BPH. Alfuzosin blocks these receptors. This results in relaxation of the muscles in the bladder and prostate, improves urine flow, and relieves the symptoms of BPH.

How the Body Affects Alfuzosin
Alfuzosin reaches a maximum concentration in the blood approximately eight hours after dosing. Food increases absorption of alfuzosin by 50% compared to the fasting state. Thus, alfuzosin is more effective when taken with a meal.

Alfuzosin undergoes extensive metabolism by the liver, with only 11% of the administered dose excreted unchanged in the urine. CYP3A4 is the primary liver enzyme involved in this metabolism. Alfuzosin is metabolized through three different pathways that produce compounds with no physiological activity.

After metabolism, 69% of the original dose is excreted in the feces and 24% is excreted in the urine.

 Side Effects
The following side effects were reported by between 1% and 2% of patients receiving alfuzosin in clinical trials:
 
Gastrointestinal
    - abdominal pain
    - acid reflux
    - constipation
    - nausea

Reproductive
    - impotence

Respiratory
    - bronchitis
    - inflammation in the sinuses or pharynx
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