Cabergoline (Generic Dostinex / Cabaser) :: Parkinson & Alzheimer :: Prescriptions

Description

Cabaser 1 mg tablets are white, oval, 3.8 x 7.4mm and concave with one side scored and engraved '7' on the left and '01' on the right.

Cabergoline tablets, for oral administration, contain 1 mg of Cabergoline. Inactive ingredients consist of leucine, USP, and lactose, NF.

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Cabergoline (Generic Dostinex / Cabaser) (20 tabs bottle) 1 mg

Quantity	Price per item	Price	Returning customer price	Bonuses
x 20 tabs	$85.00	$85.00	$76.50		Out of stock

Description

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Therapeutic indications

Treatment of Parkinson's disease

If treatment with a dopamine agonist is being considered, cabergoline is indicated as second line therapy in patients who are intolerant or fail treatment with a non-ergot compound, as monotherapy, or as adjunctive treatment to levodopa plus dopa-decarboxylase inhibitor, in the management of the signs and symptoms of Parkinson's disease.

Treatment should be initiated under specialist supervision. The benefit of continued treatment should be regularly reassessed taking into account the risk of fibrotic reactions and valvulopathy

Method of administration

The tablets are for oral administration.

Since the tolerability of dopaminergic agents is improved when administered with food, it is recommended that Cabaser be taken with meals.

Cabaser is intended for chronic, long term treatment.

Adults and elderly patients

As expected for dopamine agonists, dose response for both efficacy and side effects appears to be linked to individual sensitivity. Optimization of dose should be obtained through slow initial dose titration, from starting doses of 1 mg daily. The dosage of concurrent levodopa may be gradually decreased, while the dosage of Cabaser is increased, until the optimum balance is determined. In view of the long half-life of the compound, increments of the daily dose of 0.5-1 mg should be done at weekly (initial weeks) or bi-weekly intervals, up to optimal doses.

The recommended therapeutic dosage is 2 to 3 mg/day for patients with signs and symptoms of Parkinson's disease. Cabaser should be given as a single daily dose.

Use in children

The safety and efficacy of Cabaser have not been investigated in children as Parkinson's disease does not affect this population.

Contraindications

- Hypersensitivity to cabergoline, other ergot alkaloids or to any of the excipients.

- History of pulmonary, pericardial and retroperitoneal fibrotic disorders.

- For long-term treatment: Evidence of cardiac valvulopathy as determined by pre-treatment echocardiography.

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