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Sofradex (Dexamethasone, Framycetin, Gramicidin)

Sofradex (Dexamethasone, Framycetin, Gramicidin)

Description

Sofradex (Dexamethasone, Framycetin, Gramicidin) this preparation contains three ingredients, dexamethasone, framycetin and gramicidin. It is used to treat inflammatory conditions of the ear or eye, particularly those at risk of becoming infected.
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Sofradex 5 ml
Manufacturer: Aventis Pharma Limited, India
Brand name: Sofradex
Generic name: Dexamethasone, Framycetin, Gramicidin
Delivery time: Approx. 14-21 days
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 		 Price per item Price
 		 Returning customer price Bonuses
 		  
1 Bottle(s) $9.20 $9.20 $8.28  
5 Bottle(s) $9.20 $46.00 $41.40  
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Viral, fungal, tuberculous or purulent conditions of the eye. Use is contraindicated if glaucoma is present or herpetic keratitis (e.g. dendritic ulcer) is considered a possibility. Use of topical steroids in the latter condition can lead to extension of the ulcer and marked visual deterioration.

Dexamethasone belongs to a group of medicines, known as corticosteroids, used for reducing inflammation. Inflammation occurs as a result of allergy or irritation and is caused by the release of substances that are important in the immune system. These substances cause blood vessels to widen, resulting in the affected area becoming red, swollen, itchy and painful. Corticosteroids work by acting within cells to decrease the release of these substances in a particular area, thereby reducing swelling, redness and itch. Framycetin sulphate belongs to a group of antibiotics called aminoglycosides. These antibiotics have the ability to destroy a wide variety of bacteria. Framycetin binds to components in the bacterial cell, which results in the production of abnormal proteins. These proteins are normally necessary for the bacteria's survival, therefore the production of abnormal proteins is ultimately fatal to the bacteria.Gramicidin is also an antibacterial medicine. The combination of these two antibiotics provides treatment against a wide variety of bacteria that may infect inflamed eye or ear conditions.



Topical corticosteroids should never be given for an undiagnosed red eye as inappropriate use is potentially blinding.

Treatment with corticosteroid/antibiotic combinations should not be continued for more than 7 days in the absence of any clinical improvement, since prolonged use may lead to occult extension of infections due to the masking effect of the steroid. Prolonged use may also lead to skin sensitisation and the emergence of resistant organisms.

Prolonged use may lead to the risk of adrenal suppression in infants.

Treatment with corticosteroid preparations should not be repeated or prolonged without regular review to exclude raised intraocular, pressure, cataract formation or unsuspected infections.

Aminoglycosides antibiotics may cause irreversible, partial or total deafness when given systemically or when applied topically to open wounds or damaged skin. This effect is dose related and is enhanced by renal or hepatic impairment. Although this effect has not been reported following ocular use, the possibility should be considered when high dose topical is given to small children or infants.

How to use dexamethasone with framycetin and gramicidin drops

    * Before beginning treatment, read the manufacturer's printed information leaflet.
    * Apply these drops into the ear or eye exactly as directed by your doctor.

FOR USE IN THE EYE:

   1. Wash your hands well.
   2. Remove the outer cap.
   3. Tilt the head back and pull the lower lid of the eye down to form a pocket.
   4. Hold the container between the thumb and middle finger of the other hand, turn the container upside down near to the eye. Try not to touch the eye with the container.
   5. Apply enough pressure to the container to release one to two drops.
   6. Close the eye, and keep it closed for one to two minutes.
   7. If you think that you have missed the eye, then insert another drop.
   8. Repeat in the other eye if you have been instructed to use this preparation in both eyes.
   9. Replace the outer cap on the container. Try not to touch the tip of the container with your fingers.
  10. Wash your hands again.

FOR USE IN THE EAR:
If you find it more comfortable, you may warm the eardrops to body temperature by holding the container in your hand for a few minutes before using.

   1. Wash you hands, then clean the ear with warm water and dry thoroughly.
   2. Remove the outer cap.
   3. Lie down or tilt your head so that the affected ear faces upwards.
   4. Gently pull the earlobe to straighten the ear canal.
   5. Hold the container between the thumb and middle finger of the other hand and turn the container upside down near to the ear. Try not to touch the inside of the ear with the container.
   6. Apply enough pressure to the container to release four to five drops.
   7. Keep the ear facing upwards for a few minutes to allow the solution to come into contact with the affected area.
   8. Repeat in the other ear if you have been instructed to use these drops in both ears.
   9. Replace the outer cap on the container .
  10. Wash your hands again.
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