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Common name
Fraxiparine (Nadroparin)
Description
Nadroparin prevents and treats deep vein thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs.
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Active Ingredients:
Nadroparin
Therapeutic actions:
Nadroparin is an anticoagulant/antithrombotic drug with high anti-Xa activity (95 to 130 IU/mg), but relative to unfractionated heparin has a low inhibitory effect on factor IIa activity. (The ratio of anti-Xa to anti-IIa activity for nadroparin is 2.5 to 4, whereas it is 1 for heparin.) This greater ratio of anti-Xa activity to anti-IIa activity has the potential to provide equivalent antithrombotic efficacy with reduced hemorrhagic complications. It has both immediate and prolonged antithrombotic action.
What is it used for?:
Prophylaxis of thromboembolic disorders (particularly deep vein thrombosis and pulmonary embolism) in general surgery and in orthopedic surgery.
Treatment of deep vein thrombosis.
Prevention of clotting during hemodialysis.
Contraindications and cautions:
any unusual or allergic reaction to nadroparin or any other substances, such as foods, preservatives, or dyes;
Nadroparin has not been shown to cause birth defects or other problems in humans or animals. However, before taking this medicine, inform your doctor if you are pregnant or if you may become pregnant.
Abortion (risk of) or
Bleeding problems or
Eye problems caused by diabetes or high blood pressure or
Heart infection or
High blood pressure or
Injury or surgery involving the brain, ears, eyes, or spinal cord or
Liver disease or
Low blood platelet count or
Stomach or intestinal ulcer or
StrokeThe risk of bleeding may be increased
Kidney disease
Side effects:
More common
Deep, pain, dark purple bruise, or swelling at place of injection
Rare
Back pain; black, tarry stools; blue-green to black skin discoloration; bluish discoloration, flushing, or redness of skin; bleeding from the mouth or gums; blood in the urine; burning, pricking, tickling, or tingling sensation; coughing; swelling of eyelids, face, or lips; dizziness or feeling faint; fever; hives; itching; leg weakness; nosebleed; numbness; paralysis; problems with bladder or bowel function; redness or sloughing of skin at place of injection; skin rash; difficulty in swallowing; small purple or red spots in the mouth, on the gums, or on the skin; tightness in chest, troubled breathing, and/or wheezing; vomiting of blood or coffee ground-like material
Interactions:
ASA and other salicylate drugs, nonsteroidal anti-inflammatory drugs increase the risk of hemorrhage because of the effect on platelets. Similarly, antiplatelet drugs increase the risk of hemorrhage because of the inhibition of the platelet function
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Fraxiparine brands
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Manufacturer |
Price |
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Fraxiparine 0,3ml
10 pre-filled syringes (0.3 ml)
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Laboratoire GlaxoSmithKline, France |
$89.00 |
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Fraxiparine 0,6ml
10 pre-filled syringes (0.6 ml)
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Laboratoire GlaxoSmithKline, France |
$179.00 |
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Fraxiparine 0,8ml
10 pre-filled syringes (0.8 ml)
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Laboratoire GlaxoSmithKline, France |
$199.00 |
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