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Common name
Metindol retard
Synonyms: Indocid Sr, Indomycin, Inmeycin, Amuno, Argun, Arthrexin, Artracin, Artrinovo, Artrivia, BonidinBonidon, Catlep, Confortid, Dolcidium, Dolovin, Durametacin, Elmetacin, Hicin, Idomethine, Imbrilon, Inacid, Indomecol, Indomo, Indoptic, IndorektalInflazon,
Description
Active Ingredients:
Indomethacin
Therapeutic actions:
METINDOL (INDOMETHACIN) belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the production of a chemical (prostaglandin) which the body produces in response to injury or certain diseases. This prostaglandin would otherwise go on to cause swelling, pain and inflammation. All the medicines in this group reduce inflammation caused by the bodyis own immune system and are effective pain killers.
What is it used for?
• Abdominal pain associated with menstrual periods (dysmenorrhoea)
• Acute gout
• Inflammation of joints
• Muscle pain (myalgia)
• Pain
• Pain following surgery
• ankylosing spondylitis
• osteoarthritis
• soft tissue injuries such as tendinitis and bursitis.
Contraindications and cautions:
Taking an NSAID can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).
NSAIDs can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects.
Do not use this medication if you are allergic to indomethacin, or if you have a history of allergic reaction to aspirin or other NSAIDs.
Contraindications and cautions:
• a history of heart attack, stroke, or blood clot;
• heart disease, congestive heart failure, high blood pressure;
• a history of stomach ulcers or bleeding;
• liver or kidney disease,
• a seizure disorder such as epilepsy;
• asthma;
• polyps in your nose;
• a bleeding or blood clotting disorder;
• if you smoke.
If you have any of these conditions, you may not be able to use indomethacin, or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking indomethacin during the last 3 months of pregnancy may result in birth defects. Do not take indomethacin during pregnancy unless your doctor has told you to. Indomethacin passes into breast milk and may affect a nursing baby. Do not take indomethacin without first talking to your doctor if you are breast-feeding a baby. Do not give this medicine to a child younger than 14 years old without the advice of a doctor.
Side effects:
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
• Headache
• Heartburn or indigestion (dyspepsia)
• Nausea with or without vomiting
• Dizziness.
• Diarrhea
• Abdominal pain (or stomach pain)
• Constipation
• Spinning sensation (vertigo)
• Excessive tiredness
• Depression
• Fatigue
Interactions:
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
Especially pay attention to the following drugs:
• Other nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin), naproxen (Aleve, Anaprox, Naprosyn, Naprelan), diclofenac (Cataflam, Voltaren), oxaprozin (Daypro), celecoxib (Celebrex), etodolac (Lodine, Lodine XL), meloxicam (Mobic), and others
• Warfarin (Coumadin, Jantoven)
• Aspirin
• Lithium (Eskalith, Lithane, Lithonate, Lithotabs)
• Diuretics, such as torsemide (Demadex), furosemide (Lasix), hydrochlorothiazide
• Angiotensin-converting enzyme inhibitors (ACE inhibitors) such as lisinopril (Zestril, Prinivil), fosinopril (Monopril), captopril (Capoten), quinapril (Accupril), benazepril (Lotensin?), enalapril (Vasotec), and ramipril (Altace)
• Beta blockers, such as metoprolol (Lopressor), propranolol (Inderal), atenolol (Tenormin), and metoprolol (Toprol XL)
• Methotrexate (Rheumatrex, Trexall)
• Cyclosporine (Gengraf, Neoral, Sandimmune)
• Diflunisal (Dolobid)
• Corticosteroids, such as prednisone, hydrocortisone (Cortef), dexamethasone (Decadron, Dexone, Hexadrol), and many others
• Probenecid (Benemid, Probalan).
Several herbal and nutritional supplements can also interact with Indocin and may increase the risk of bleeding. Examples of these include (but are not limited to):
• Dong quai
• Feverfew
• Garlic
• Ginger
• Ginkgo biloba
• Ginseng
• St. Johnis wort
• Fish oil supplements
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Metindol retard brands
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Product |
Manufacturer |
Price |
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Indometacin
30 tablets (25 mg/tablet)
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Actavis, France |
$12.00 |
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Indometacin gel
1 tube (5%) (30 gr)
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Universal Farm, Romania |
$9.00 |
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Indometacin ointment
1 tube (10%) (40 gr)
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Balkanpharma Troyan AD, Bulgaria |
$12.00 |
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Metindol retard
50 tablets (75 mg/tablet)
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ICN Polfa Rzeszow, Poland |
$24.00 |
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