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Common name
Zofran (Ondansetron)
Description
Zofran belongs to a group of medicines called serotonin receptor-3 antagonists. Some medical treatments can make you feel sick or be sick (nausea and vomiting) - Zofran may stop these effects.
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Active Ingredients:
Ondansetron
Therapeutic actions:
Zofran is an antiemetic drug that works by reducing the activity of the vagus nerve which normally activates the vomiting center in medula oblongata and inhibits serotonin receptors that are triggered by chemotherapy. It does not manifest any effect on motion sickness or on dopamin and muscarinic receptors.
What is it used for?:
(Indications:)
Zofran is used in prevention of nausea and vomiting caused by various conditions:
• Chemotherapy induced states
• Hyperemesis gravidarum in pregnancy
• Cyclic vomiting syndrome
• Postoperative state
Contraindications and cautions:
Consult your doctor if you can use Ondansetron in the following cases:
• Hypersensitivity to Ondansetron or to other similar drugs.
• Liver disorders
• History of allergic reactions to any drugs or foods
• Long QT syndrome(heart problems)
• Phenylketonuria Ondansetron has been assigned to FDA pregnancy category B. Consult your doctor before using it during pregnancy.
Side effects:
There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Zofran will experience it or any other.
The side-effects include:
• Allergic reactions
• Vision impairment
• Fever
• decreased heart rate, problems breathing normally
• Agitation, shivers
• Fainting, light-headedness
• decreased urination
Other more common side-effects include:
• Diarrhea or constipation
• Tiredness
• Headache
• Dizziness
The side effects listed above may not include all of the side effects reported by the drug is manufacturer. For more information about any other possible risks associated with Zofran, please read the information provided with Ondansetron or consult your doctor or pharmacist.
Interactions:
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with Zofran. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe.
Especially mention the following groups of drugs:
• Anti-epileptic
• Barbiturates
• Pain relief medications
• Anti-psychotic medications
• Antibiotic
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