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Common name
Imunofan
Description
Imunofan is a medication used for treatment of immunological disorders including immunodeficiency. It is indicated for use as a prophylactic and treatment of immunodeficient states with multiple etiology and diseases followed by immune disorders in adult and children. Imunofan is a clear, colorless solution for injections provided in ampoules, which contains as an active pharmacological substance hexapeptide Arg-a-Asp-Lys-Val-Tyr-Arg with molecular weight 836 D.
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Brief description:
Imunofan is a medication used for treatment of immunological disorders including immunodeficiency. It is indicated for use as a prophylactic and treatment of immunodeficient states with multiple etiology and diseases followed by immune disorders in adult and children. Imunofan is a clear, colorless solution for injections provided in ampoules, which contains as an active pharmacological substance hexapeptide Arg-a-Asp-Lys-Val-Tyr-Arg with molecular weight 836 D.
Therapeutic actions:
Imunofan generates the triggering signal in the target-cells. The preparation is quickly and completely absorbed at the site of administration and is rapidly cleaved to amino acids. Imunofan increases and regulates immunoreaction of human organism and participates in the processes of inactivation of free radicals. Therefore, pharmacological impact of this medication is based on two primary effects ?C immunocorrection (i.e. correction of deficiency of the immune system) and normalization of the oxidative processes of the organism.
What is it used for?:
(Indications:)
Carcinogenesis
Imunofan is an effective drug-component in the treatment of patients with local tumors subjected to complex radical therapy such as surgery, chemo- and radiation therapy. It may be used for both the prevention and the correction of side effects of anticancer treatment. The medication should be used before and after the course of chemo-radiotherapy. It may be indicated in the patients with disseminated (IV stage) cancer for symptomatic therapy, cancer intoxication treatment and improvement oncological patients quality of life. Imunofan may be an effective drug-component in children suffers from acute and chronic oncohematologic diseases: lymphoblastic lymphadenosis, acute lymphadenosis, malignant lymphoma, lymphogranulomatosis subjected to chemotherapy and complicated toxic or viral hepatitis, pneumonia, sepsis. It may be used in complex therapy of children with papillomatosis larynx.
Acute and Chronic Pyogenic Infections
Imunofan is a drug of choice, that may be used in combination with specific anti-bacterial therapy, in the treatment of toxic, viral and traumatic disorders of the blood stream, meningitis, heart, lung, joints, liver and pancreas, complicated by septic and/or pyemic microorganisms.
Opportunistic Infections
It may be indicated in serious infections caused by strains of the following organisms, when interferon-a or other drugs of pathogenetic therapy are ineffective or contraindicated:
Cytomegalovirus Toxoplasma gondii Klebsiella pneumonia
Herpes virus Chlamydiae Cryptococcus neoformans
HIV-infectious
Imunofan may be an effective drug-component in the treatment of different stages of AIDS to complex chemotherapy. It causes an effective protection of the immune system from the damaging effects of the free radical compounds with following improvement of Th1/Th2 balance, decreasing of tumor necrosis factor (TNF) production and reduction of manifestation the toxic reactions.
Acute and Chronic Viral Hepatitis
Imunofan is a drug of choice in the treatment of hepatitis B and C that may be used in patients with contraindication to interferon therapy and high activity of pathological process in liver. Imunofan administration leads to decrease of transaminase activity and decrease the level of bilirubin. The activation of antiviral immunity under the action of the preparation leads to decrease of viral expression.
Diphtheria
Imunofan is a drug of choice that may be used in the patients with allergic reactions and contradiction to diphtheria antitoxin treatment.
Vaccination
Imunofan is an effective immunologic adjuvant that may be used in combination with specific vaccination (absorbed diphtheria and tetanus toxoid with low content of antigen) of the patients with heavy allergic diseases.
Psoriasis
It may be an effective drug-component in the treatment of different variations psoriasis to complex therapy.
Contraindications and cautions:
Tell your doctor your medical history, especially Rh-incompatible pregnancy, autoimmune diseases. Imunofan is a sterile solution; for parenteral use only Contradictions Rh-incompatible pregnancy, idiosyncrasy.
Side effects:
Although unlikely, Imunofan may cause insignificant inflammatory reactions in certain individuals. Therefore, before using this drug, tell your doctor if you have any autoimmune diseases or drug idiosyncrasy.
Interactions:
Inform your doctor about the medicines you may use (both prescription and nonprescription). Avoid use of any drugs affecting immunomodulation or biostimulation, including alcohol.
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