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Common name
Garamycin (Gentamicin)
Description
Ophthalmic, an antibiotic, is applied to the eye for treatment of infections such as conjunctivitis (pinkeye) and other eye infections.
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Active Ingredients:
Gentamicin
Therapeutic actions:
Treating serious infections caused by certain bacteria. Garamycin Solution is an aminoglycoside antibiotic. It works by slowing the growth of, or killing, sensitive bacteria. Inhibits production of bacterial protein, causing bacterial cell death.
What is it used for?:
(Indications:)
Short-term treatment of serious infections caused by susceptible strains of microorganisms, especially gram-negative bacteria; adjunct to systemic gentamicin in serious CNS infections (intrathecal); treatment of superficial ocular infections (ophthalmic); treatment of primary (eg, impetigo contagiosa) and secondary (eg, infectious eczemafoid dermatitis) skin infections; skin cysts and superficial skin infections, infection prophylaxis, and aid to healing (topical).
Contraindications and cautions:
Do NOT use Garamycin Solution if:
* you are allergic to any ingredient in Garamycin Solution or another aminoglycoside antibiotic (eg, tobramycin)
* you are taking fludarabine, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), or nondepolarizing muscle relaxants (eg, atracurium) Contact your doctor or health care provider right away if any of these apply to you. Some medical conditions may interact with Garamycin Solution.
Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
* if you are pregnant, planning to become pregnant, or are breast-feeding
* if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
* if you have allergies to medicines, foods, or other substances
* if you have myasthenia gravis (a condition in which the muscles become progressively paralyzed) or Parkinson disease
* if you have dehydration, hearing problems, kidney failure, or you are a child younger than 9 years of age with diarrhea, or a stomach or intestinal infection
Side effects:
CNS Headache; dizziness; vertigo; encephalopathy; confusion; fever; lethargy; convulsions; muscle weakness and twitching; peripheral neuropathy; acute organic brain syndrome; depression; pseudotumor cerebri; increased CSF protein; arachnoiditis or burning at injection site after intrathecal administration. Dermatologic Rash; urticaria; itching; anaphylaxis; photosensitivity (topical). EENT Blurred vision; tinnitus; hearing loss; mydriasis and conjunctival paresthesia (ophthalmic). GI Nausea; vomiting. Genitourinary Oliguria; proteinuria; increased serum creatinine and BUN; casts; Fanconi-like syndrome. Hematologic Anemia; eosinophilia; leukopenia; thrombocytopenia; granulocytopenia. Hepatic Elevated LFT results. Respiratory Apnea; pulmonary fibrosis. Miscellaneous Pain and irritation at injection site; splenomegaly; hypomagnesemia; hyponatremia; hypocalcemia; hypokalemia.
Interactions:
Some MEDICINES MAY INTERACT with Garamycin Solution.
Tell your health care provider if you are taking any other medicines, especially any of the following:
* Polypeptide antibiotics (eg, polymyxin B) because breathing may stop and kidney damage may occur
* Cephalosporins, cyclosporine, fludarabine, loop diuretics (eg, furosemide), methoxyflurane, nitrosoureas (eg, carmustine), NSAIDs (eg, ibuprofen), or vancomycin because the risk of Garamycin Solution's side effects, including kidney damage or hearing loss, may be increased
* Nondepolarizing muscle relaxants (eg, atracurium) or succinylcholine because the risk of their side effects may be increased by Garamycin Solution
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