|
 Actual product may differ in
appearance from image shown. |
Common name
Cinnotropil (piracetam and cinnarizine)
Description
Cinnotropil capsules of piracetam and cinnarizine is an association between a modulator of the cerebral neurotransmission and an inhibitor of smooth muscle contraction by calcium channel blocking.
more about this product >>
Active Ingredients:
(piracetam and cinnarizine)
Therapeutic actions:
Piracetam is a nootropic agent. It improves the metabolic processes in the brain cells, possesses an antihypoxic action, accelerates the reparative processes in functionally damaged cells after traumas, intoxications, and stoke. Piracetam acts selectively on the telencephalon, improving its associative functions. The drug has an antiplatelet and a microcirculation ameliorating action.
The therapeutic effect of Piracetam is manifested after prolonged treatment (several weeks to several months).
Cinnarizine inhibits contractions of vascular smooth muscle cells by blocking calcium channels.
Cinnarizine increases erythrocyte deformability and decreases blood viscosity in vitro.
Cinnarizine inhibits stimulation of the vestibular system.
Cinnarizine belongs to a group of medicines called antihistamines.
Cinnarizine works by blocking histamine and muscarinic receptors in the vomiting center in the brain. This prevents the vomiting center from receiving nerve messages from the vestibular apparatus. In turn, this prevents disturbances in the middle ear from activating the vomiting center and causing nausea, vertigo and vomiting.
What is it used for?:
(Indications:)
The product is indicated in the treatment of psycho-organic syndromes of various etiology, such as:
- acute and chronic cerebrovascular conditions
- cerebral trauma
- comatous and subcomatous states, after intoxications and cerebral trauma
- labyrinthic disorders, vertigo, tinnitus, nistagmus, nausea and vomiting (including movement illness)
- Meniere syndrome
- cerebral infarct, encephalopathy with chronic hypertonia
- vascular dementia, psychogenic disorders related to memory,attention and focus disorders, emotional liability
- psycho limitation syndrome accompanied by symptoms of asthenia and adynamia
- childrens intellectual development stopping
- migraine prophylaxis
Contraindications and cautions:
First trimester of pregnancy; severe parenchymal liver or kidney diseases; agitated depression, particularly in the elderly. Special warnings and precautions In patients suffering from liver diseases, a monitoring of the liver enzymes and function is necessary. In patients with renal failure, the 24-hours dose should be adjusted according to the creatinine clearance. The levels of the residual nitrogen and creatinine should be checked regularly.
Because of the distribution into breast milk the breast-feeding should be discontinued for the period of the treatment. make sure your doctor or pharmacist knows:
If you are pregnant, trying for a baby or breast-feeding.
If you suffer from hypotension (low blood pressure)
If you suffer from heart, liver or prostate problems
If you suffer from Parkinson's disease
If you have problems urinating (passing water)
If you suffer from glaucoma
If you suffer from epilepsy
If you suffer from porphyria (a blood disorder)
You should not use this medication in:
Children under five years of age
Hereditary blood disorders called porphyrias
Rare hereditary problems of fructose or galactose intolerance, Lapp lactose deficiency, glucose-galactose malabsorption or sucrase-isomaltase insufficiency (Stugeron tablets contain lactose and sucrose).
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
Use with caution in:
Decreased kidney function
Decreased liver function
Parkinson's disease.
Side effects:
Rarely in susceptible patients can be observed the following symptoms: increased aggressiveness, headache, sleep disturbance, gastrointestinal problems, blood pressure instability. The most common antihistaminic side-effect of cinnarizine is sedation which can vary from slight drowsiness to deep sleep, and including inability to concentrate, lassitude, dizziness, and inco-ordination.
Sedative effects, when they occur, may diminish after a few days.
gastro-intestinal disturbances such as nausea, vomiting, diarrhoea or constipation, anorexia or increased appetite and epigastric pain. Somnolence and gastro-intestinal disturbances are usually transient and may often be prevented by achieving the optimum dosage gradually.
Central effects may include muscular weakness, headache and euphoria.
Cinnarizine may also produce antimuscarinic effects such as blurred vision, difficulty in micturition, dysuria, dryness of mouth and tightness of chest.
Weight gain, perspiration or allergic reactions may be observed. Cases of lichen planus and lupus-like symptoms and an isolated case of cholestatic jaundice have been reported. In elderly people cases of aggravation or an appearance of extrapyramidal symptoms sometimes associated with depressive feelings have been described during prolonged therapy.
The treatment should be discontinued in such cases.
Abnormal movements of the hands, legs, face, neck and tongue, eg tremor, twitching, rigidity (rarely with long-term use, mostly in elderly people - stop taking this medicine and consult your doctor if this occurs)
Skin reactions (very rarely with long-term use)
Jaundice (very rarely with long-term use) The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Interactions:
Piracetam increases the effects of the drugs stimulating the CNS, thyroid hormones and oral anticoagulants. The concurrent administration of neuroleptics increases the risk of hyperkinesia. It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe. Cinnarizine may enhance the sedative effect of central nervous system depressants including alcohol, barbiturates, hypnotics, narcotic analgesics, tricyclic antidepressants, sedatives and tranquillisers.
The side-effects of anticholinergic substances such as atropine and tricyclic
Antidepressants may be enhanced by the concomitant administration of antihistamines. Monoamine-oxidase inhibitors may enhance the antimuscarinic effects of antihistamines. There may be an increased risk of drowsiness if this medicine is taken with any of the following (which can also cause drowsiness):
alcohol
antipsychotics, eg chlorpromazine
benzodiazepines, eg diazepam, temazepam
sedating antihistamines, eg chlorphenamine, promethazine
sleeping tablets, eg zopiclone
strong opioid painkillers, eg morphine, codeine
tricyclic antidepressants, eg amitriptyline
<< Close
|
 |
|
 |
|
Cinnotropil brands
|
Product |
Manufacturer |
Price |
|
| |
 |
Cinnotropil
60 capsules (400/25 mg/capsule)
|
Rompharm Company, Romania |
$12.00 |
|
|
|
| |
|
Neuro-Norm
60 capsules (400/25 mg/capsule)
|
Darnita, Ukraine |
$16.00 |
|
|
|
| |
|
Phezam
60 capsules (400/25 mg/capsule)
|
Balkanpharma Dupnitza AD, Bulgaria |
$16.00 |
|
|
|
|
|
 |
|
 |
|
|
