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Common name
Theo SR (Theophylline)
Description
Theo SR (Theophylline) is a xanthine derivative. It works by relaxing the smooth muscle surrounding the bronchial tubes (air passages) of the lungs, allowing the tubes to widen, making breathing easier. Theo SR (Theophylline) improves contraction of the diaphragm (the major breathing muscle).
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Active Ingredients:
Theophylline
Therapeutic actions:
Theo SR (Theophylline) increases cAMP accumulation in tissues, blocks adenosine (purine) receptors; reduces inflow of calcium ions through cellular membranes canals, reduces contractive activity of unstriated muscles. Theo SR (Theophylline) relaxes muscles of bronchial tubes, blood vessels (mainly vessels of brain, skin and kidneys); increases renal blood flow, possesses moderately expressed diuretic effect. The drug stabilizes the interseptum of mast cells, brakes mediators of allergic reactions release. Increases mucociliary clearance, stimulates diaphragm arctation, improves function of respiratory and intercostal muscles, stimulates the respiratory center. Normalizing respiratory function, it promotes blood saturation and decrease in carbonic acid concentration; stimulates the centers of aspiration. Theo SR (Theophylline) intensifies lung ventilation in hypokalemia conditions.
What is it used for?:
Broncho-obstructive syndrome of various genesis: bronchial asthma, chronic obstructive bronchitis. Pulmonary hypertensia, pulmonary heart, edema syndrome of nephritic genesis (as a part of the combined therapy), paroxysmal nocturnal dyspnea.
Contraindications and cautions:
• Epilepsy;
• peptic ulcer disease during recrudescence;
• gastritis with hyperacidity;
• recent GIT hemorrhage;
• serious arterial hyper- and hypotension;
• serious tachyarrythmia;
• apoplectic shock;
• retinal hemorrhage;
• children under 3 y.o.;
• Hypersensitivity to Theo SR (Theophylline) and to other xanthine derivants (caffeine, pentoxifylline, teobromine).
Side effects:
CNS: giddiness, headache, sleeplessness, excitation, anxiety, irritability, tremor.
CVS: palpitation, tachycardia (also fetal tachycardia in III trimester), arrhythmia, hypotension, angina spuria, increase of heart strokes frequency.
Digestive system: gastrodynia, nausea, emesis, esophageal reflux, heartburn, peptic ulcer recrudescence, diarrhea, anorexia.
Allergic reactions: skin eruption, itching, fever.
Other: chest pain, tachypnea, albuminuria, hematuria, hypoglycemia, dieresis increase, hyperhidrosis.
Side effects decrease when dose decline.
Interactions:
Theo SR (Theophylline) interacts with a wide variety of drugs. Consult your doctor before combining any other medication with Theo SR.
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