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Common name
Ceclor (Cefaclor)
Description
Cefaclor is in a group of drugs called cephalosporin (SEF a low spor in) antibiotics. It works by fighting bacteria in your body.
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Active Ingredients:
Cefaclor
Therapeutic actions:
Inhibits bacterial
cell wall synthesis by binding to one or more of the penicillin-binding
proteins (PBPs) which in turn inhibits the final transpeptidation step of
peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall
biosynthesis. Bacteria eventually lyse due to ongoing activity of cell wall
autolytic enzymes (autolysins and murein hydrolases) while cell wall assembly
is arrested.
What is it used for?:
Ceclor, a
cephalosporin antibiotic, is used in the treatment of ear, nose, throat,
respiratory tract, urinary tract, and skin infections caused by specific
bacteria, including staph, strep, and E. coli. Uses include treatment of
sore or strep throat, pneumonia, and tonsillitis. Ceclor CD, an extended
release form of the drug, is also used for flare-ups of chronic bronchitis.
Contraindications and cautions:
Do not take this medication if you are allergic to
cefaclor or to other cephalosporin antibiotics, such as:
cefadroxil (Duricef); cefdinir (Omnicef); cefditoren
(Spectracef); cefixime (Suprax); cefprozil (Cefzil); ceftazidime (Fortaz); cefuroxime
(Ceftin); cephalexin (Keflex); and others.
Do not take Ceclor
if you have a history of gastrointestinal problems, particularly bowel
inflammation (colitis).
Side effects:
Serious:
* diarrhea that is watery or bloody;
* fever, sore throat, and joint pain with a severe blistering, peeling, and red skin rash;
* numbness or tingly feeling;
* warmth, redness, or tingling under your skin;
* swelling in your hands or feet;
* fast or pounding heartbeats;
* chest pain, shortness of breath.
Less serious:
* mild nausea, stomach pain, constipation, loss of appetite;
* anxiety, drowsiness;
* increased night-time urination;
* headache;
* runny nose, sore throat, cough; or
* vaginal itching or discharge.
Interactions:
Ceclor may interact with the following medicines:
* Antacids containing magnesium or aluminum, including Gelusil, Maalox, and Mylanta (interact with Ceclor CD only);
* Certain antibiotics such as Amikin;
* Certain potent diuretics such as Edecrin and Lasix;
* Probenecid (Benemid);
* Warfarin (Coumadin).
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