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Common name
Ceptaz (Ceftazidime)
Description
Ceftazidime is in a
group of drugs called cephalosporin (SEF a low spor in) antibiotics. It works
by fighting bacteria in your body. Ceftazidime injection is used to treat many
kinds of bacterial infections, including severe or life-threatening forms.
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Active Ingredients:
Ceftazidime
Therapeutic actions:
Ceptaz has a bactericidal effect; action depends on ability to reach and bind penicillin-binding proteins located in bacterial cytoplasmic membranes. Cephalosporins inhibit bacterial septum and cell wall synthesis, probably by acylation of membrane-bound transpeptidase enzymes. This prevents cross-linkage of peptidoglycan chains, which is necessary for bacterial cell wall strength and rigidity. Also, cell division and growth are inhibited, and elongation of susceptible bacteria and lysis frequently occur. Rapidly dividing bacteria are those most susceptible to the action of cephalosporins.
What is it used for?:
• Lower Respiratory Tract Infections, including pneumonia;
• Skin and Skin Structure Infections;
• Urinary Tract Infections, both complicated and uncomplicated;
• Bacterial Septicemia;
• Bone and Joint Infections;
• Gynecologic Infections, including endometritis, pelvic cellulitis, and other infections of the female genital tract;
• Intra abdominal Infections, including peritonitis;
• Central Nervous System Infections, including meningitis.
Contraindications and cautions:
• Allergy to ceftazidime, or to similar antibiotics, such as Ceclor, Ceftin, Cefzil, Duricef, Keflex, Omnicef, Spectracef, Suprax, and others.
• Before using this medication, tell your doctor if you are allergic to any drugs (especially penicillin). Also tell your doctor if you have liver or kidney disease, diabetes, heart failure, cancer, a stomach or intestinal disorder, or if you are malnourished.
Side effects:
Serious side effects: diarrhea that is watery or bloody; fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; swelling, pain, or irritation where the injection was given; cold feeling, discoloration, or skin changes in your fingers; seizure (black-out or convulsions); white patches or sores inside your mouth or on your lip; jaundice (yellowing of the eyes or skin).
Less serious side effects: nausea, vomiting, diarrhea, stomach pain; headache, dizziness; numbness or tingly feeling; vaginal itching or discharge.
Interactions:
• Ceftazidime can make birth control pills less effective;
• chloramphenicol (Chloromycetin);
• diuretics (water pills) such as furosemide (Lasix); or
• an antibiotic such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Mycifradin, Neo-Fradin, Neo-Tab), netilmicin (Netromycin), streptomycin, or tobramycin (Nebcin, Tobi).
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